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Role of Phosphoinositide 3-Kinase and Endocytosis in Nerve Growth Factor-Induced Extracellular Signal-Regulated Kinase Activation via Ras and Rap1

Neurotrophins promote multiple actions on neuronal cells including cell survival and differentiation. The best-studied neurotrophin, nerve growth factor (NGF), is a major survival factor in sympathetic and sensory neurons and promotes differentiation in a well-studied model system, PC12 cells. To me...

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Detalhes bibliográficos
Main Authors: York, Randall D., Molliver, Derek C., Grewal, Savraj S., Stenberg, Paula E., McCleskey, Edwin W., Stork, Philip J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86417/
https://ncbi.nlm.nih.gov/pubmed/11027277
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