Replication past O(6)-Methylguanine by Yeast and Human DNA Polymerase η
O(6)-Methylguanine (m6G) is formed by the action of alkylating agents such as N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) on DNA. m6G is a highly mutagenic and carcinogenic lesion, and it presents a block to synthesis by DNA polymerases. Here, we provide genetic and biochemical evidence for the invo...
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| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2000
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027270/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.21.8001-8007.2000 |
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