Down-Regulation of Cyclin D1 Expression by Prostaglandin A(2) Is Mediated by Enhanced Cyclin D1 mRNA Turnover

Prostaglandin A(2) (PGA(2)), an experimental chemotherapeutic agent, causes growth arrest associated with decreased cyclin D1 expression in several cancer cell lines. Here, using human non-small-cell lung carcinoma H1299 cells, we investigated the mechanisms whereby PGA(2) down-regulates cyclin D1 e...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lin, Shankung, Wang, Wengong, Wilson, Gerald M., Yang, Xiaoling, Brewer, Gary, Holbrook, Nikki J., Gorospe, Myriam
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027261/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.21.7903-7913.2000
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