Essential Roles for Ankyrin Repeat and Transactivation Domains in Induction of T-Cell Leukemia by Notch1

Notch receptors participate in a conserved signaling pathway that controls the development of diverse tissues and cell types, including lymphoid cells. Signaling is normally initiated through one or more ligand-mediated proteolytic cleavages that permit nuclear translocation of the intracellular por...

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Bibliographic Details
Main Authors: Aster, Jon C., Xu, Lanwei, Karnell, Fredrick G., Patriub, Vytas, Pui, John C., Pear, Warren S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86303/
https://ncbi.nlm.nih.gov/pubmed/11003647
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