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Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem Cells

Achieving long-term retroviral expression in primary cells has been problematic. De novo DNA methylation of infecting proviruses has been proposed as a major cause of this transcriptional repression. Here we report the development of a mouse stem cell virus (MSCV) long terminal repeat-based retrovir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cherry, Sara R., Biniszkiewicz, D., van Parijs, L., Baltimore, D., Jaenisch, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86295/
https://ncbi.nlm.nih.gov/pubmed/11003639
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