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Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem Cells

Achieving long-term retroviral expression in primary cells has been problematic. De novo DNA methylation of infecting proviruses has been proposed as a major cause of this transcriptional repression. Here we report the development of a mouse stem cell virus (MSCV) long terminal repeat-based retrovir...

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Hlavní autoři: Cherry, Sara R., Biniszkiewicz, D., van Parijs, L., Baltimore, D., Jaenisch, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86295/
https://ncbi.nlm.nih.gov/pubmed/11003639
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