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c-Src Signaling Induced by the Adapters Sin and Cas Is Mediated by Rap1 GTPase

Oncogenic Src proteins have been extensively studied to gain insight into the signaling mechanisms of Src. To better understand signaling through wild-type Src, we used an approach that involves activation of Src signaling through the binding of physiologic ligands to the Src SH3 domain. To this end...

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Main Authors: Xing, Luzhou, Ge, Chang, Zeltser, Ross, Maskevitch, Gregory, Mayer, Bruce J., Alexandropoulos, Konstantina
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC86290/
https://ncbi.nlm.nih.gov/pubmed/10982853
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