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Vav2 Activates Rac1, Cdc42, and RhoA Downstream from Growth Factor Receptors but Not β1 Integrins

The Rho family of GTPases plays a major role in the organization of the actin cytoskeleton. These G proteins are activated by guanine nucleotide exchange factors that stimulate the exchange of bound GDP for GTP. In their GTP-bound state, these G proteins interact with downstream effectors. Vav2 is a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Betty P., Burridge, Keith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC86269/
https://ncbi.nlm.nih.gov/pubmed/10982832
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