Hsp72-Mediated Suppression of c-Jun N-Terminal Kinase Is Implicated in Development of Tolerance to Caspase-Independent Cell Death

Pretreatment with mild heat shock is known to protect cells from severe stress (acquired thermotolerance). Here we addressed the mechanism of this phenomenon by using primary human fibroblasts. Severe heat shock (45°C, 75 min) of the fibroblasts caused cell death displaying morphological characteris...

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Bibliographic Details
Main Authors: Gabai, Vladimir L., Yaglom, Julia A., Volloch, Vladimir, Meriin, Anatoli B., Force, Thomas, Koutroumanis, Maria, Massie, Bernard, Mosser, Dick D., Sherman, Michael Y.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86215/
https://ncbi.nlm.nih.gov/pubmed/10958679
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