Human Genomic Sequences That Inhibit Splicing

Mammalian genes are characterized by relatively small exons surrounded by variable lengths of intronic sequence. Sequences similar to the splice signals that define the 5′ and 3′ boundaries of these exons are also present in abundance throughout the surrounding introns. What causes the real sites to...

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Main Authors: Fairbrother, William G., Chasin, Lawrence A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86212/
https://ncbi.nlm.nih.gov/pubmed/10958678
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