ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis-Acting Element Responsible for the Mammalian Unfolded Protein Response

Transcription of genes encoding molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) is induced by accumulation of unfolded proteins in the ER. This intracellular signaling, known as the unfolded protein response (UPR), is mediated by the cis-acting ER stress response element (...

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Autores principales: Yoshida, Hiderou, Okada, Tetsuya, Haze, Kyosuke, Yanagi, Hideki, Yura, Takashi, Negishi, Manabu, Mori, Kazutoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC86199/
https://ncbi.nlm.nih.gov/pubmed/10958673
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