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Functions of E2A-HEB Heterodimers in T-Cell Development Revealed by a Dominant Negative Mutation of HEB

Lymphocyte development and differentiation are regulated by the basic helix-loop-helix (bHLH) transcription factors encoded by the E2A and HEB genes. These bHLH proteins bind to E-box enhancers in the form of homodimers or heterodimers and, consequently, activate transcription of the target genes. E...

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Pubblicato in:Mol Cell Biol
Autori principali: Barndt, Robert J., Dai, Meifang, Zhuang, Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.18.6677-6685.2000
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