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Functions of E2A-HEB Heterodimers in T-Cell Development Revealed by a Dominant Negative Mutation of HEB

Lymphocyte development and differentiation are regulated by the basic helix-loop-helix (bHLH) transcription factors encoded by the E2A and HEB genes. These bHLH proteins bind to E-box enhancers in the form of homodimers or heterodimers and, consequently, activate transcription of the target genes. E...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Barndt, Robert J., Dai, Meifang, Zhuang, Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.18.6677-6685.2000
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