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The SH3 Domain Directs Acto-Myosin-Dependent Targeting of v-Src to Focal Adhesions via Phosphatidylinositol 3-Kinase

The v-Src oncoprotein is translocated to integrin-linked focal adhesions, where its tyrosine kinase activity induces adhesion disruption and cell transformation. We previously demonstrated that the intracellular targeting of Src is dependent on the actin cytoskeleton, under the control of the Rho fa...

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Fincham, Valerie J., Brunton, Valerie G., Frame, Margaret C.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6518-6536.2000
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