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The SH3 Domain Directs Acto-Myosin-Dependent Targeting of v-Src to Focal Adhesions via Phosphatidylinositol 3-Kinase

The v-Src oncoprotein is translocated to integrin-linked focal adhesions, where its tyrosine kinase activity induces adhesion disruption and cell transformation. We previously demonstrated that the intracellular targeting of Src is dependent on the actin cytoskeleton, under the control of the Rho fa...

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Pubblicato in:Mol Cell Biol
Autori principali: Fincham, Valerie J., Brunton, Valerie G., Frame, Margaret C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6518-6536.2000
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