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The SH3 Domain Directs Acto-Myosin-Dependent Targeting of v-Src to Focal Adhesions via Phosphatidylinositol 3-Kinase

The v-Src oncoprotein is translocated to integrin-linked focal adhesions, where its tyrosine kinase activity induces adhesion disruption and cell transformation. We previously demonstrated that the intracellular targeting of Src is dependent on the actin cytoskeleton, under the control of the Rho fa...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Fincham, Valerie J., Brunton, Valerie G., Frame, Margaret C.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6518-6536.2000
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