Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7

Recent studies implicate the interferon (IFN) regulatory factors (IRF) IRF-3 and IRF-7 as key activators of the alpha/beta IFN (IFN-α/β) genes as well as the RANTES chemokine gene. Using coexpression analysis, the human IFNB, IFNA1, and RANTES promoters were stimulated by IRF-3 coexpression, whereas...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Lin, Rongtuan, Génin, Pierre, Mamane, Yaël, Hiscott, John
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6342-6353.2000
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