Rap2 as a Slowly Responding Molecular Switch in the Rap1 Signaling Cascade

Rap2 is a member of the Ras family of GTPases and exhibits 60% identity to Rap1, but the function and regulation of Rap2 remain obscure. We found that, unlike the other Ras family proteins, the GTP-bound active form exceeded 50% of total Rap2 protein in adherent cells. Guanine nucleotide exchange fa...

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Detalhes bibliográficos
Main Authors: Ohba, Yusuke, Mochizuki, Naoki, Matsuo, Keiko, Yamashita, Shigeko, Nakaya, Mie, Hashimoto, Yuko, Hamaguchi, Michinari, Kurata, Takeshi, Nagashima, Kazuo, Matsuda, Michiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86083/
https://ncbi.nlm.nih.gov/pubmed/10913189
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