Rap2 as a Slowly Responding Molecular Switch in the Rap1 Signaling Cascade

Rap2 is a member of the Ras family of GTPases and exhibits 60% identity to Rap1, but the function and regulation of Rap2 remain obscure. We found that, unlike the other Ras family proteins, the GTP-bound active form exceeded 50% of total Rap2 protein in adherent cells. Guanine nucleotide exchange fa...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Ohba, Yusuke, Mochizuki, Naoki, Matsuo, Keiko, Yamashita, Shigeko, Nakaya, Mie, Hashimoto, Yuko, Hamaguchi, Michinari, Kurata, Takeshi, Nagashima, Kazuo, Matsuda, Michiyuki
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10913189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.16.6074-6083.2000
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