Species-Specific Elements in the Large T-Antigen J Domain Are Required for Cellular Transformation and DNA Replication by Simian Virus 40

The J domain of simian virus 40 (SV40) large T antigen is required for efficient DNA replication and transformation. Despite previous reports demonstrating the promiscuity of J domains in heterologous systems, results presented here show the requirement for specific J-domain sequences in SV40 large-...

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Hlavní autoři: Sullivan, Christopher S., Tremblay, James D., Fewell, Sheara W., Lewis, John A., Brodsky, Jeffrey L., Pipas, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86052/
https://ncbi.nlm.nih.gov/pubmed/10891510
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