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Species-Specific Elements in the Large T-Antigen J Domain Are Required for Cellular Transformation and DNA Replication by Simian Virus 40

The J domain of simian virus 40 (SV40) large T antigen is required for efficient DNA replication and transformation. Despite previous reports demonstrating the promiscuity of J domains in heterologous systems, results presented here show the requirement for specific J-domain sequences in SV40 large-...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Sullivan, Christopher S., Tremblay, James D., Fewell, Sheara W., Lewis, John A., Brodsky, Jeffrey L., Pipas, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2000
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10891510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.15.5749-5757.2000
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