Phosphorylation of Tyrosine Residues in the Kinase Domain and Juxtamembrane Region Regulates the Biological and Catalytic Activities of Eph Receptors

Members of the Eph family of receptor tyrosine kinases exhibit a striking degree of amino acid homology, particularly notable in the kinase and membrane-proximal regions. A mutagenesis approach was taken to address the functions of specific conserved tyrosine residues within these catalytic and juxt...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Binns, Kathleen L., Taylor, Paul P., Sicheri, Frank, Pawson, Tony, Holland, Sacha J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4791-4805.2000
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