Bcl-2 Retards Cell Cycle Entry through p27(Kip1), pRB Relative p130, and Altered E2F Regulation

Independent of its antiapoptotic function, Bcl-2 can, through an undetermined mechanism, retard entry into the cell cycle. Cell cycle progression requires the phosphorylation by cyclin-dependent kinases (Cdks) of retinoblastoma protein (pRB) family members to free E2F transcription factors. We have...

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書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Vairo, Gino, Soos, Timothy J., Upton, Todd M., Zalvide, Juan, DeCaprio, James A., Ewen, Mark E., Koff, Andrew, Adams, Jerry M.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2000
主題:	Cell Growth and Development
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85901/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10848600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.13.4745-4753.2000
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