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Mutations in the Bare Lymphocyte Syndrome Define Critical Steps in the Assembly of the Regulatory Factor X Complex

The regulatory factor X (RFX) complex, which contains RFXANK(B), RFXAP, and RFX5, binds to X and S boxes in major histocompatibility complex class II (MHC II) promoters. In the bare lymphocyte syndrome (BLS), which is a human severe combined immunodeficiency, MHC II promoters are neither occupied no...

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Detalhes bibliográficos
Main Authors: Nekrep, Nada, Jabrane-Ferrat, Nabila, Peterlin, B. Matija
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85813/
https://ncbi.nlm.nih.gov/pubmed/10825209
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