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Mechanism of Caffeine-Induced Checkpoint Override in Fission Yeast

Mitotic checkpoints restrain the onset of mitosis (M) when DNA is incompletely replicated or damaged. These checkpoints are conserved between the fission yeast Schizosaccharomyces pombe and mammals. In both types of organisms, the methylxanthine caffeine overrides the synthesis (S)-M checkpoint that...

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Bibliografische gegevens
Hoofdauteurs: Moser, Bettina A., Brondello, Jean-Marc, Baber-Furnari, Beth, Russell, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85796/
https://ncbi.nlm.nih.gov/pubmed/10825192
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