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Mechanism of Caffeine-Induced Checkpoint Override in Fission Yeast

Mitotic checkpoints restrain the onset of mitosis (M) when DNA is incompletely replicated or damaged. These checkpoints are conserved between the fission yeast Schizosaccharomyces pombe and mammals. In both types of organisms, the methylxanthine caffeine overrides the synthesis (S)-M checkpoint that...

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Hlavní autoři: Moser, Bettina A., Brondello, Jean-Marc, Baber-Furnari, Beth, Russell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85796/
https://ncbi.nlm.nih.gov/pubmed/10825192
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