S-Phase Progression Mediates Activation of a Silenced Gene in Synthetic Nuclei

Aberrant expression of developmentally silenced genes, characteristic of tumor cells and regenerating tissue, is highly correlated with increased cell proliferation. By modeling this process in vitro in synthetic nuclei, we find that DNA replication leads to deregulation of established developmental...

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Detaylı Bibliyografya
Asıl Yazarlar: Crowe, Alison J., Piechan, Julie L., Sang, Ling, Barton, Michelle C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Transcriptional Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC85786/
https://ncbi.nlm.nih.gov/pubmed/10805758
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