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Alu element-mediated gene silencing
The Alu elements are conserved ∼300-nucleotide-long repeat sequences that belong to the SINE family of retrotransposons found abundantly in primate genomes. Pairs of inverted Alu repeats in RNA can form duplex structures that lead to hyperediting by the ADAR enzymes, and at least 333 human genes con...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435129/ https://ncbi.nlm.nih.gov/pubmed/18497743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.94 |
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