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Alu element-mediated gene silencing

The Alu elements are conserved ∼300-nucleotide-long repeat sequences that belong to the SINE family of retrotransposons found abundantly in primate genomes. Pairs of inverted Alu repeats in RNA can form duplex structures that lead to hyperediting by the ADAR enzymes, and at least 333 human genes con...

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Hlavní autoři: Chen, Ling-Ling, DeCerbo, Joshua N, Carmichael, Gordon G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435129/
https://ncbi.nlm.nih.gov/pubmed/18497743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.94
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