Altered Activity, Social Behavior, and Spatial Memory in Mice Lacking the NTAN1p Amidase and the Asparagine Branch of the N-End Rule Pathway

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. N-terminal asparagine and glutamine are tertiary destabilizing residues, in that they are enzymatically deamidated to yield secondary destabilizing residues aspartate and glutamate, which are conjuga...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kwon, Yong Tae, Balogh, Seth A., Davydov, Ilia V., Kashina, Anna S., Yoon, Jeong Kyo, Xie, Youming, Gaur, Arti, Hyde, Lynn, Denenberg, Victor H., Varshavsky, Alexander
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.11.4135-4148.2000
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