Somatic mRNA Turnover Mutants Implicate Tristetraprolin in the Interleukin-3 mRNA Degradation Pathway

Control of mRNA stability is critical for expression of short-lived transcripts from cytokines and proto-oncogenes. Regulation involves an AU-rich element (ARE) in the 3′ untranslated region (3′UTR) and cognate trans-acting factors thought to promote either degradation or stabilization of the mRNA....

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Bibliografske podrobnosti
Main Authors: Stoecklin, Georg, Ming, Xiu-Fen, Looser, Renate, Moroni, Christoph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC85689/
https://ncbi.nlm.nih.gov/pubmed/10805719
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