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Role of the Mitochondrial Hsp70s, Ssc1 and Ssq1, in the Maturation of Yfh1

The mitochondrial matrix of the yeast Saccharomyces cerevisiae contains two molecular chaperones of the Hsp70 class, Ssc1 and Ssq1. We report that Ssc1 and Ssq1 play sequential roles in the import and maturation of the yeast frataxin homologue (Yfh1). In vitro, radiolabeled Yfh1 was not imported int...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Voisine, Cindy, Schilke, Brenda, Ohlson, Maikke, Beinert, Helmut, Marszalek, Jaroslaw, Craig, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3677-3684.2000
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