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Role of the Mitochondrial Hsp70s, Ssc1 and Ssq1, in the Maturation of Yfh1

The mitochondrial matrix of the yeast Saccharomyces cerevisiae contains two molecular chaperones of the Hsp70 class, Ssc1 and Ssq1. We report that Ssc1 and Ssq1 play sequential roles in the import and maturation of the yeast frataxin homologue (Yfh1). In vitro, radiolabeled Yfh1 was not imported int...

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Detalhes bibliográficos
Main Authors: Voisine, Cindy, Schilke, Brenda, Ohlson, Maikke, Beinert, Helmut, Marszalek, Jaroslaw, Craig, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85660/
https://ncbi.nlm.nih.gov/pubmed/10779357
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