Multiple Mechanisms Control Phosphorylation of PHAS-I in Five (S/T)P Sites That Govern Translational Repression

Control of the translational repressor, PHAS-I, was investigated by expressing proteins with Ser/Thr → Ala mutations in the five (S/T)P phosphorylation sites. Results of experiments with HEK293 cells reveal at least three levels of control. At one extreme is nonregulated phosphorylation, exemplified...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Mothe-Satney, Isabelle, Yang, Daqing, Fadden, Patrick, Haystead, Timothy A. J., Lawrence, John C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.10.3558-3567.2000
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