QR Code

Methylation of the Cyclin A1 Promoter Correlates with Gene Silencing in Somatic Cell Lines, while Tissue-Specific Expression of Cyclin A1 Is Methylation Independent

Gene expression in mammalian organisms is regulated at multiple levels, including DNA accessibility for transcription factors and chromatin structure. Methylation of CpG dinucleotides is thought to be involved in imprinting and in the pathogenesis of cancer. However, the relevance of methylation for...

Full description

Saved in:
Published in:Mol Cell Biol
Main Authors: Müller, Carsten, Readhead, Carol, Diederichs, Sven, Idos, Gregory, Yang, Rong, Tidow, Nicola, Serve, Hubert, Berdel, Wolfgang E., Koeffler, H. Phillip
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10757815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.9.3316-3329.2000
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items