Stress Signals Utilize Multiple Pathways To Stabilize p53
The p53 tumor suppressor is activated by many diverse stress signals through mechanisms that result in stabilization and accumulation of the p53 protein. p53 is normally degraded through the proteasome following interaction with MDM2, which both functions as a ubiquitin ligase for p53 and shuttles t...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10757806/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.9.3224-3233.2000 |
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