Role of Genotypic Analysis of the Thymidine Kinase Gene of Herpes Simplex Virus for Determination of Neurovirulence and Resistance to Acyclovir

Mutations in the thymidine kinase (TK) gene of herpes simplex virus (HSV) have been associated with resistance to acyclovir (ACY) and possible recognition of neurotropic strains. We sequenced a 335-bp segment of the TK gene to determine the frequency of mutations in HSV strains recovered from dermal...

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保存先:
書誌詳細
主要な著者: Lee, N. Y., Tang, Y.-W., Espy, M. J., Kolbert, C. P., Rys, P. N., Mitchell, P. S., Day, S. P., Henry, S. L., Persing, D. H., Smith, T. F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
Virology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC85520/
https://ncbi.nlm.nih.gov/pubmed/10488172
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