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Defects in tRNA Processing and Nuclear Export Induce GCN4 Translation Independently of Phosphorylation of the α Subunit of Eukaryotic Translation Initiation Factor 2

Induction of GCN4 translation in amino acid-starved cells involves the inhibition of initiator tRNA(Met) binding to eukaryotic translation initiation factor 2 (eIF2) in response to eIF2 phosphorylation by protein kinase GCN2. It was shown previously that GCN4 translation could be induced independent...

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Wedi'i Gadw mewn:
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Qiu, Hongfang, Hu, Cuihua, Anderson, James, Björk, Glenn R., Sarkar, Srimonti, Hopper, Anita K., Hinnebusch, Alan G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2000
Pynciau:
Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2505-2516.2000
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