c-Myc Proteolysis by the Ubiquitin-Proteasome Pathway: Stabilization of c-Myc in Burkitt's Lymphoma Cells

The c-Myc oncoprotein is a transcription factor which is a critical regulator of cellular proliferation. Deregulated expression of c-Myc is associated with many human cancers, including Burkitt's lymphoma. The c-Myc protein is normally degraded very rapidly with a half-life of 20 to 30 min. Here we...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Gregory, Mark A., Hann, Stephen R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2000
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85426/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2423-2435.2000
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