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c-Myc Overexpression Uncouples DNA Replication from Mitosis

c-myc has been shown to regulate G(1)/S transition, but a role for c-myc in other phases of the cell cycle has not been identified. Exposure of cells to colcemid activates the mitotic spindle checkpoint and arrests cells transiently in metaphase. After prolonged colcemid exposure, the cells withdraw...

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Detalhes bibliográficos
Main Authors: Li, Qing, Dang, Chi V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84377/
https://ncbi.nlm.nih.gov/pubmed/10409725
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