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c-Myc Overexpression Uncouples DNA Replication from Mitosis

c-myc has been shown to regulate G(1)/S transition, but a role for c-myc in other phases of the cell cycle has not been identified. Exposure of cells to colcemid activates the mitotic spindle checkpoint and arrests cells transiently in metaphase. After prolonged colcemid exposure, the cells withdraw...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Qing, Dang, Chi V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1999
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84377/
https://ncbi.nlm.nih.gov/pubmed/10409725
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