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Modulation of DNA Binding Protein Affinity Directly Affects Target Site Demethylation

It has recently been shown that in Xenopus, DNA demethylation at promoter regions may involve protein-DNA interactions, based on the specificity of the demethylated sites. Utilizing a stable episomal system in human cells, we recently mapped the sites and dissected the steps of demethylation at oriP...

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Autors principals: Lin, Iping G., Tomzynski, Thomas J., Ou, Qinglin, Hsieh, Chih-Lin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85401/
https://ncbi.nlm.nih.gov/pubmed/10713158
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