Transcription-Coupled Translation Control of AML1/RUNX1 Is Mediated by Cap- and Internal Ribosome Entry Site-Dependent Mechanisms

AML1/RUNX1 belongs to the runt domain transcription factors that are important regulators of hematopoiesis and osteogenesis. Expression of AML1 is regulated at the level of transcription by two promoters, distal (D) and proximal (P), that give rise to mRNAs bearing two distinct 5′ untranslated regio...

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Bibliografiska uppgifter
Huvudupphovsmän: Pozner, Amir, Goldenberg, Dalia, Negreanu, Varda, Le, Shu-Yun, Elroy-Stein, Orna, Levanon, Ditsa, Groner, Yoram
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC85390/
https://ncbi.nlm.nih.gov/pubmed/10713153
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