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Transcription-Coupled Translation Control of AML1/RUNX1 Is Mediated by Cap- and Internal Ribosome Entry Site-Dependent Mechanisms

AML1/RUNX1 belongs to the runt domain transcription factors that are important regulators of hematopoiesis and osteogenesis. Expression of AML1 is regulated at the level of transcription by two promoters, distal (D) and proximal (P), that give rise to mRNAs bearing two distinct 5′ untranslated regio...

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Udgivet i:Mol Cell Biol
Principais autores: Pozner, Amir, Goldenberg, Dalia, Negreanu, Varda, Le, Shu-Yun, Elroy-Stein, Orna, Levanon, Ditsa, Groner, Yoram
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713153/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2297-2307.2000
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