Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors

Notch receptors participate in a highly conserved signaling pathway that regulates morphogenesis in multicellular animals. Maturation of Notch receptors requires the proteolytic cleavage of a single precursor polypeptide to produce a heterodimer composed of a ligand-binding extracellular domain (N(E...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Rand, Matthew D., Grimm, Lisa M., Artavanis-Tsakonas, Spyros, Patriub, Vytas, Blacklow, Stephen C., Sklar, Jeffrey, Aster, Jon C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1825-1835.2000
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