Sequential Requirements of the N-Terminal Palmitoylation Site and SH2 Domain of Src Family Kinases in the Initiation and Progression of FcɛRI Signaling

Initial biochemical signaling originating from high-affinity immunoglobulin E receptor (FcɛRI) has been ascribed to Src family kinases. To understand the mechanisms by which individual kinases drive the signaling, we conducted reconstitution experiments: FcɛRI signaling in RBL2H3 cells was first sup...

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Autores principales: Honda, Zen-ichiro, Suzuki, Takeshi, Kono, Hajime, Okada, Masato, Yamamoto, Tadashi, Ra, Chisei, Morita, Yutaka, Yamamoto, Kazuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC85358/
https://ncbi.nlm.nih.gov/pubmed/10669752
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