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Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-jun Promoter and to Cellular Transformation

The serine/threonine kinase Cot is a member of the mitogen-activated protein kinase (MAPK) kinase kinase family implicated in cellular transformation. Enhanced expression of this protein has been shown to activate both the MAPK and the c-Jun N-terminal kinase (JNK) pathways and to stimulate the nucl...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Chiariello, Mario, Marinissen, Maria Julia, Gutkind, J. Silvio
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1747-1758.2000
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