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TATA-Binding Protein Mutants That Increase Transcription from Enhancerless and Repressed Promoters In Vivo

Using a genetic screen, we isolated three TATA-binding protein (TBP) mutants that increase transcription from promoters that are repressed by the Cyc8-Tup1 or Sin3-Rpd3 corepressors or that lack an enhancer element, but not from an equivalently weak promoter with a mutated TATA element. Increased tr...

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Bibliografiska uppgifter
Huvudupphovsmän: Geisberg, Joseph V., Struhl, Kevin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC85312/
https://ncbi.nlm.nih.gov/pubmed/10669725
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