TATA-Binding Protein Mutants That Increase Transcription from Enhancerless and Repressed Promoters In Vivo

Using a genetic screen, we isolated three TATA-binding protein (TBP) mutants that increase transcription from promoters that are repressed by the Cyc8-Tup1 or Sin3-Rpd3 corepressors or that lack an enhancer element, but not from an equivalently weak promoter with a mutated TATA element. Increased tr...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Geisberg, Joseph V., Struhl, Kevin
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1478-1488.2000
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