Trypanosoma brucei Guide RNA Poly(U) Tail Formation Is Stabilized by Cognate mRNA

Guide RNAs (gRNAs) are small RNAs that provide specificity for uridine addition and deletion during mRNA editing in trypanosomes. Terminal uridylyl transferase (TUTase) adds uridines to pre-mRNAs during RNA editing and adds a poly(U) tail to the 3′ end of gRNAs. The poly(U) tail may stabilize the as...

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Bibliografiske detaljer
Main Authors: McManus, Michael T., Adler, Brian K., Pollard, Victoria W., Hajduk, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85205/
https://ncbi.nlm.nih.gov/pubmed/10629045
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