Trypanosoma brucei Guide RNA Poly(U) Tail Formation Is Stabilized by Cognate mRNA

Guide RNAs (gRNAs) are small RNAs that provide specificity for uridine addition and deletion during mRNA editing in trypanosomes. Terminal uridylyl transferase (TUTase) adds uridines to pre-mRNAs during RNA editing and adds a poly(U) tail to the 3′ end of gRNAs. The poly(U) tail may stabilize the as...

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Détails bibliographiques
Auteurs principaux: McManus, Michael T., Adler, Brian K., Pollard, Victoria W., Hajduk, Stephen L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC85205/
https://ncbi.nlm.nih.gov/pubmed/10629045
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