Modulated Binding of SATB1, a Matrix Attachment Region Protein, to the AT-Rich Sequence Flanking the Major Breakpoint Region of BCL2

The t(14,18) chromosomal translocation that occurs in human follicular lymphoma constitutively activates the BCL2 gene and disrupts control of apoptosis. Interestingly, 70% of the t(14,18) translocations are confined to three 15-bp clusters positioned within a 150-bp region (major breakpoint region...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Ramakrishnan, Meera, Liu, Wen-Man, DiCroce, Patricia A., Posner, Aleza, Zheng, Jian, Kohwi-Shigematsu, Terumi, Krontiris, Theodore G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10629043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.3.868-877.2000
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